The Detroit Lions will play without two high draft picks in rookie cornerbacks Terrion Arnold and Ennis Rakestraw Jr. while possibly getting back veteran Emmanuel Moseley against the host Indianapolis Colts on Sunday.Arnold was downgraded Saturday from questionable to out because of a groin injury. He was limited at practice on Thursday and participated in a full practice on Friday.The Lions drafted Arnold with the 24th overall pick of the 2024 NFL Draft out of Alabama. Arnold, 21, has started all 10 games and has 38 tackles and six passes defended.Rakestraw (hamstring) was placed on injured reserve after not practicing all week. He already had been ruled out for Sunday’s game.Detroit picked Rakestraw in the second round (61st overall) out of Missouri. He has played in eight games and has six tackles. Rakestraw, 22, has played on 46 defensive snaps (8 percent) and 95 special teams snaps (42 percent).Moseley had full practice sessions all week and was activated from injured reserve on Saturday but was listed as questionable for Sunday.The 28-year-old is in his second season with Detroit and appeared in one game last season before going on IR in October 2023. He was placed on IR on Aug. 27 with a designation to return.